donald resler

A comprehensive laboratory guide to peptide storage and stability — covering degradation pathways, lyophilised vs reconstituted storage, freeze-thaw best practices, and sequence-specific considerations.

Peptide purity is fundamental to reproducible research. This guide explains what HPLC purity means, types of synthesis impurities, how to read a CoA, and purity thresholds for different research applications.

A practical research guide to lyophilisation — why peptides are freeze-dried, how the process preserves them, and a step-by-step protocol for reconstitution and storage in laboratory settings.

NAD+ is the essential electron carrier linking the TCA cycle to mitochondrial ATP synthesis. This research overview covers the mitochondrial NAD+ pool, SIRT3 regulation, and age-related mitochondrial decline.

A deep-dive into how NAD+ fuels sirtuin deacylase enzymes, what published longevity research reveals about this relationship, and why it matters for aging biology research.

GHK-Cu copper peptide stimulates collagen synthesis, regulates MMPs, and activates dermal fibroblasts through multiple mechanisms. A detailed research overview of its skin remodelling biology.

TB-500 (Thymosin Beta-4) operates through actin cytoskeletal regulation, cell migration, and angiogenic pathways. This research overview covers its mechanisms and key study models.

A detailed examination of BPC-157’s signalling mechanisms across gastrointestinal, vascular, and peripheral tissue repair systems — including nitric oxide pathways and growth factor modulation.

A receptor-level comparison of Semaglutide, Tirzepatide, and Retatrutide — covering structural differences, signalling profiles, and research compound selection guidance.

A research-focused overview of how GIP and GLP-1 incretin hormones coordinate appetite suppression, insulin secretion, and glucose homeostasis — and why they are central to metabolic peptide science.